After sequencing fragments of DNA to obtain reads, most genomic pipelines follow one of two steps. The reads can be de novo assembled to construct longer stretches called contigs from scratch, with ...
Metagenome sequencing of 'tricky' gene pools has been ridden with issues during assembly of sequenced DNA fragments, which can now be addressed by a tool developed by scientists. This hybrid ...
Study assesses eight de novo genome assembly software tools on viral next-generation sequencing data
A new study compares and assesses eight de novo genome assembly software tools on actual viral next-generation sequencing data. The study, which includes the whole genome sequence data of SARS-CoV-2, ...
Next-generation sequencing (NGS) is widely used for microbiome analysis due to its high-throughput and cost-effective nature. NGS utilizes short read lengths, which allow for more efficient and ...
Over the brief history of next-generation sequencing (NGS), methods for the creation of libraries for the various NGS instrument platforms have evolved considerably and continue to be in a constant ...
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