Clinical Oncology Pharmacist, Ann B. Barshinger Cancer Institute, Lancaster, Pennsylvania Mirtazapine is a tetracyclic antidepressant approved by the US Food and Drug Administration for the treatment ...

Cachexia is common in cancer, yet it is poorly understood in noncancer diagnoses. In this article, Carlson and Dahlin review cancer cachexia in cardiac disease. The definition, pathophysiology, and ...

A study describes the generation of a new mouse model that could lead to a better understanding of the cachexia syndrome. A study published in Cell Reports Aug. 6 describes the generation of a new ...

In 2011, Laura Beaver did not let the growing tumor in her body dictate her life. She kept up her normal hourlong gym routine. She took weekend bike rides near her Washington state home. She did the ...

Cachexia is a process that accompanies many chronic diseases, and consists of a combination of wasting of lean body mass, increased energy expenditure, and a paradoxical loss of appetite. Cachexia ...

Cancer ravages both body and mind. If you've ever lost loved ones to the disease, you might recognize the physical and emotional changes cancer patients often endure during their final months. They ...

A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This ...

Ponsegromab increased weight and activity levels in cachexia patients, confirming GDF-15 as a key driver and therapeutic target. Significant weight gain was observed in ponsegromab-treated groups ...

Please provide your email address to receive an email when new articles are posted on . Patients with cancer cachexia assigned ponsegromab gained significantly more weight than those assigned placebo.

A multidisciplinary team of researchers has identified Upd3, a cytokine, as an important modulator of tumor growth and host wasting via activation of JAK/STAT signaling. Cancer therapy has shown ...

Cachexia is a paraneoplastic syndrome of unintentional adipose and muscle tissue wasting with severe impacts to functionality and quality of life. Although health inequities across minority and ...