Engineered dendritic cells capture tumor EVs, enhancing antigen presentation and T cell activation to boost cancer immunotherapy in preclinical models.

Cardiovascular Reparative Medicine and Tissue Engineering (CRMTE) aims to develop future technologies and therapeutic strategies that will serve as treatment for cardiovascular disease. CRMTE includes ...

Portal Biotechnologies and Multiply Labs announced a collaboration with the goal of leveraging automation to accelerate product timelines and reduce costs, helping innovative cell therapies reach more ...

Regenerative medicine combines tissue engineering and cell therapies to repair or replace damaged human tissues and organs. Key applications include treating osteoarthritis with mesenchymal stem cells ...

Cells can now be genetically programmed to record their histories within their genomes, a development that could revolutionize the study of developmental and disease processes, according to a ...

When immune cells go awry and spark inflammation, a different type of immune cell stands ready to counteract that effect and return the immune system to a state of balance. Therapies based on such ...

Bioengineers have developed a new construction kit for building custom sense-and-respond circuits in human cells. The research could revolutionize therapies for complex conditions like autoimmune ...

Around the same time that Rosenberg assembled an army of the most successful T cells he could find, others developed strategies to arm these immune soldiers. The field of cell engineering took off in ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...