Chronic stress can trigger major depressive disorder through peripheral immune factors. Enhanced circulating levels of complement component 3 (C3), a key innate immunity molecule that is predominantly ...
Over 300 million people worldwide suffer from major depressive disorder (MDD). Unfortunately, only 30–40% of patients with MDD achieve complete remission after conventional monoamine antidepressant ...
On the cover: In this issue of Cell Genomics, Borbye-Lorenzen et al. examine the correlates of circulating C3 and C4 protein concentrations in 68,768 neonates and the risk of mental and autoimmune ...