The complement system protects against infection, positively responds to tissue damage, clears cell debris, directs and modulates the adaptive immune system, and functions in neuronal development, ...
Louse-borne relapsing fever (LBRF), a neglected vector-borne disease, is solely caused by Borrelia (B.) recurrentis 1. Historically responsible for deadly epidemics, LBRF remains endemic in countries ...
The complement system has more than 50 soluble and membrane-bound proteins. In innate and adaptive immunity, complement is essential for eliminating foreign pathogens and apoptotic cells. It is also ...
The story of Q32 Bio, a company that develops therapeutics for inflammatory and autoimmune diseases, started two decades ago. That's when V. Michael Holers, MD, a University of Colorado School of ...
Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...