AlphaFold is making great progress in protein structure prediction, not only for single-chain proteins but also for multi-chain protein complexes. When using AlphaFold-Multimer to predict ...

Accurately capturing domain-domain interactions is key to understanding protein function and designing structure-based drugs. Although AlphaFold2 has made a breakthrough on single domain, it should be ...

No "sticky ends"? No problem. A new study by NYU chemists finds that DNA tiles can assemble into 3D structures without the sticky cohesion of hydrogen bonding. This finding, published in Nature ...

RNA therapeutics have emerged as one of the most promising new classes of medicines. Eight small interfering RNA (siRNA) ...

Chemists have developed an efficient skeletal editing method for frequently used heteroaromatic structures. The technique could serve as a means to chemically modify biologically active compounds.

A new technique incorporates many different building blocks of cellular metamaterials into one unified graph-based representation. This can be used to make a user-friendly interface that can quickly ...

Ph.D. candidate Petr Steindl creates complex structures of light using single photons. As a teenager, he wanted to study Czech poetry but decided on quantum physics. "Looking back, I am glad I ...

We tend to view ourselves and the complex cells that build us as a distinct branch of the tree of life from the compact, ...