In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...
Synthetic gene networks in mammalian cells are currently limited to either protein-based transcription factors or RNA-based regulators. Here, we demonstrate a regulatory approach based on circular ...
Homologous recombination (HR) is central to the template-based repair of DNA double-strand breaks, maintaining genome integrity 1,2,3,4. A central reaction in HR is the strand exchange, in which the ...
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