Ultra-precise technology can count damaged DNA fragments

The Korea Research Institute of Standards and Science has developed an ultrasensitive immunoassay-based analytical platform ...
Nature

Transcription-coupled nucleotide excision repair protects against genomic instability and cell death induced by the liver toxin methyleugenol

Methyleugenol (ME) is a hepatotoxic phenylpropene naturally present in various herbs and spices. Following dietary exposure, ME undergoes metabolic activation in the liver, resulting in the formation ...
Nature

Role of the nucleotide excision repair endonuclease XPF in the kinetoplastid parasite Trypanosoma brucei

The nucleotide excision repair (NER) mechanism is responsible for removing bulky DNA damage, such as pyrimidine dimers induced by ultraviolet (UV) light. The NER pathway excises the damaged strand ...
EurekAlert!

nucleotide excision repair pathway (IMAGE)

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...