Inflammatory bowel disease (IBD) and other intestinal disorders affect millions of people worldwide, often causing lasting ...

The alternative text for this image may have been generated using AI. Overall, our work proposes a mechanism of disease tolerance 48 in ISCs and their niche whereby LXR activation functions as a ...

Radiotherapy is a crucial treatment modality for abdominal tumors, often delivered in combination with chemotherapy. However, the intensity of radiotherapy is limited by the tolerance of surrounding ...

Such systems could reduce unnecessary clinical failures and potentially complement or replace some animal testing approaches. "This study demonstrates that drug-induced intestinal damage can be ...

There is a critical unmet need to help tighten and maintain a healthy intestinal barrier and treat a leaky gut. Researchers have now found that a unique strain of probiotic bacteria, Bifidobacterium ...

Villi are tiny projections in the small intestine that absorb nutrients from food. Diseases like celiac disease and inflammatory bowel disease can damage villi and cause malabsorption. Villi are ...

Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent cells that build up over time, the treatment boosted gut regeneration, ...

(Beyond Pesticides, March 13, 2025) Study results published in Pesticide Biochemistry and Physiology “suggest that combined [pesticide] exposure may further amplify the toxicity and compromise the ...

Neotame was recently found to have no impact on appetite. But within weeks, researchers have deemed the same artificial sweetener capable of damaging the human intestine and causing illness. It’s been ...

Animal models have enabled us to learn an incredible amount of new information about human biology, health, and disease. But these animals can't always serve as a reliable example of the human body.

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...