Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...

Overview of the MuSE‑Promoter framework. The model processes raw DNA sequences through parallel branches (semantic embeddings and handcrafted features), then uses a multi‑scale CNN‑SE‑Transformer ...

A team of researchers unveils a novel, key aspect of enhancer-mediated regulation of gene expression and proposes a mechanism that explains the tight connection between gene enhancers and promoters.

As cells mature and differentiate (right), they use a much more elaborate and cell-type specific ‘switchboard’ to control their gene expression, especially when compared to earlier, immature stages ...

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

Your skin cells are clearly different from your brain cells even though they both develop in the same person and carry the same genes. They are different because each cell type expresses a particular ...