The objectives of the study were predefined. The main objective was to determine whether HMGB-1 levels at admission could identify patients with life-threatening bleeding requiring MTP activation in ...
Severe trauma poses a significant challenge to global public health. According to the Global Burden of Diseases, Injuries, and Risk Factors Study, trauma is responsible for approximately 8% of all ...
Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...