The multi-enzyme pyruvate dehydrogenase complex (PDHc) links glycolysis to the citric acid cycle and plays vital roles in metabolism, energy production, and cellular signaling. Although all components ...

N-terminal acetylation (NTA) is the most common protein modification in eukaryotes, playing a crucial role in proteostasis. Almost 40% of the human proteome is acetylated co-translationally by the ...

Description Microbial metabolism represents one of the most chemically diverse and functionally complex systems in nature. Despite decades of research, a ...

Cell-free biocatalysis is being increasingly used as a substitute for conventional chemical catalysts, given that enzymes (biological catalysts) are more sustainable and selective in the manufacture ...

For the first time, the structure of a DNA enzyme complex implicated in infertility and cancer has been obtained using cryo-electron microscopy (cryo-EM). A collaboration of researchers, led by ...