Causal inference in observational settings seeks to estimate the effect of exposures, treatments or interventions on outcomes in the absence of random assignment. Unlike experimental designs, ...

Nancy Dreyer, PhD, MPH, FISE, chief scientific advisor to Picnic Health, shares some of the ways that direct-to-patient approaches have improved observational research. Direct-to-patient approaches ...

Comparative effectiveness research increasingly is being recognized as a priority area in cancer research. Although researchers have been conducting comparative effectiveness research for decades, ...

In the article that accompanies this editorial, Lu et al 5 conducted a systematic review on the use of instrumental variable (IV) methods in oncology comparative effectiveness research. The main ...