Learn more about the “glue sniffer” protein, which is able to detect brain cells’ incoming chemical signals, and what that ...

Heterotrimeric G proteins, comprising Gα, Gβ and Gγ subunits, are central to the transduction of extracellular signals into precise intracellular responses in plants. These proteins not only regulate ...

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

The brain’s chatter has always been partly out of reach, with electrical spikes easy to record but the chemical whispers ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides ...

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum ...

The 8-Bromo-cAMP sodium salt PKA activator, a synthetic analog of cAMP, is one of the most potent tools of investigating and playing with this pathway, which has become an essential part of ...

A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

Researchers created a new kind of cancer drug that can grab a mutant protein while also carrying a second hit against the ...