The urinary system is the drainage system of the human body for removing waste and extra water. It consists of the two kidneys, two ureters (which connect the kidneys and the bladder), a bladder and a ...

Untreated UTIs in pregnancy can progress to kidney infection (pyelonephritis), trigger preterm labour, or contribute to low ...

THE clinical diagnosis of pyelonephritis is frequently overlooked, and the disparity between the clinical and post-mortem findings in this infection has been emphasized repeatedly. 1–4 The failure of ...

Tebipenem pivoxil becomes the only FDA-approved oral carbapenem for complicated UTIs/pyelonephritis in adults lacking viable ...

Acute pyelonephritis is a bacterial infection of the kidneys that affects up to 2 percent of pregnant women. In most cases, the infection first develops in the lower urinary tract. If it’s not ...

Urinary tract infections (UTIs) are a severe public health problem that are caused by a range of different pathogens. When the infection migrates to the upper urinary tract or is seeded there via ...

GSK plc GSK and its Cambridge-based partner, Spero Therapeutics SPRO, announced that the FDA has approved tebipenem pivoxil ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

It has been difficult to devise a practical clinical approach to reliably separate simple urinary tract infections (UTIs) from UTIs that also involve the kidneys (acute pyelonephritis). The gold ...

First and only oral carbapenem antibiotic approved in the USApproval based on PIVOT-PO trial demonstrating non-inferiority compared to ...

I often find myself under- or overestimating the incidence of certain nephrology-related conditions. I know this "error" is, in part, due to an "exposure bias" in my practice. I tend to overestimate ...

Montini G (2007) Antibiotic treatment for pyelonephritis in children: multicentre randomized controlled non-inferiority trial. BMJ 335: 386 Acute pyelonephritis is a serious disease, especially for ...