In fish, multiple HBD of CTR and stable ɑ-helix of calcitonin contribute to the high binding affinity and slow dissociation, thus triggering prolonged AC/cAMP signaling. In humans, RAMP dependent ...

Cellular signal transduction plays a crucial role in maintaining and regulating the balance of intracellular and extracellular environments, which largely depends on the controlled transport of ...

Netrins are a family of secretory proteins that play a role in cell migration and axon guidance during embryonic development 1. Netrin-1 is the most widely studied member of Netrins. It binds to its ...