Nature

Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction

Ovarian cancer is the most lethal gynaecological cancer and treatment options remain limited. In a recent first-in-class Phase I trial, the monoclonal IgE antibody MOv18, specific for the ...
Medical Xpress

C-reactive protein links to ventricular repolarization in coronary artery disease, study finds

A new study reveals that the predictive power of key inflammatory markers, such as C-reactive protein, shifts fundamentally depending on whether a patient suffers from cirrhosis or acute/chronic ...
EurekAlert!

C-reactive protein is closely related to cardiac repolarization in patients with coronary artery disease in contrast to patients with cirrhosis

A new study reveals that the predictive power of key inflammatory markers, such as C-reactive protein, shifts fundamentally depending on whether a patient suffers from cirrhosis or acute/chronic ...
Nature

Autophagy-induced RelB/p52 activation mediates tumour-associated macrophage repolarisation and suppression of hepatocellular carcinoma by natural compound baicalin

The plasticity of tumour-associated macrophages (TAMs) has implicated an influential role in hepatocellular carcinoma (HCC). Repolarisation of TAM towards M1 phenotype characterises an ...