A new research paper was published in Oncotarget's, titled "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation." These isoforms have been suggested as the reason for the ...

Colorectal cancer is the third most common cancer in the United States. Although screening has led to a decrease in incidence over the past 20 years, early-onset colorectal cancer has been rising.

A new research paper was published in Oncotarget's Volume 14 on April 24, 2023, entitled, "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation." Signal transducer and ...

Signal transducer and activator of transcription 3 (STAT3) plays a key role in cell proliferation observed in colorectal cancer (CRC), where up-regulation of STAT3 accelerates tumorigenesis and ...

Microenvironment and cytokines in pseudomyxoma peritonei. This is an ASCO Meeting Abstract from the 2013 Gastrointestinal Cancers Symposium. This abstract does not include a full text component. If ...

Triple-negative breast cancer (TNBC), which accounts for up to 20% of cases of breast cancer, is one of the most aggressive and difficult to treat subtypes of the disease.

Phase II clinical trial of PLX038 in patients with platinum resistant ovarian, primary peritoneal and fallopian tube cancer. A phase 1/2 study of ubamatamab (REGN4018), a MUC16×CD3 bispecific antibody ...

Precancerous cells must adapt to and overcome cellular stress and inflammation in order to progress and form malignant tumors. Now, researchers at University of California San Diego School of Medicine ...