Cucumbers, a summer staple of salads and sandwiches, are a valuable commercial crop. They also have a less well-known role as valuable model plants which are helping researchers to extend the ...

Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide ...

Single nucleotide substitutions (SNSs) are the major type of somatic variation in tumors 1,2. Even though the absolute majority of the point mutations are neutral 3, there are many examples of ...

Advancements in sequencing technology have made extensive collections of mutations and genomic information available 1,2,3,4. These datasets include millions of novel mutations that cannot all be ...