Despite the power of CRISPR in genome editing, its clinical application is limited by off-target effects; these effects are currently difficult to evaluate at the genome level but are likely to ...
In a study published in the Clinical and Translational Medicine, a Nanjing University research group evaluated the on- and off-target effects of self-assembled siRNA delivery system. RNA interference ...
Genome-editing tools, such as CRISPR–Cas systems, have shown great promise for use in life sciences and therapeutic applications. However, these tools can sometimes modify non-targeted genome regions ...
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