Medical Xpress

New AI tool could replace costly cancer gene expression profiling

A team led by Cedars-Sinai Health Sciences University investigators has created a faster, cheaper way to determine the genes expressed in cancerous tumors. The AI-based tool, which they describe in ...
ascopubs.org

RNA-Seq based gene expression profiling of baseline and on-treatment breast tumors to predict response to HER2-directed therapy, without chemotherapy (TBCRC026).

Breast Cancer Index re-stratifies 21-gene assay risk groups for late distant recurrence and extended endocrine therapy benefit: Results from the BCI Registry Study. This is an ASCO Meeting Abstract ...
Nature

Longitudinal molecular profiling elucidates immunometabolism dynamics in breast cancer

Although metabolic reprogramming within tumor cells and tumor microenvironment (TME) is well described in breast cancer, little is known about how the interplay of immune state and cancer metabolism ...
Nature

Gene expression signatures of response to fluoxetine treatment: systematic review and meta-analyses

Genomic (and other ‘omic) data have provided valuable insights on the pharmacological signatures of antidepressant response, but results from individual studies are largely heterogeneous. In this work ...
ascopubs.org

Exploring the significance of MET overexpression by gene expression profiling versus immunohistochemistry in an EGFR-mutant lung cancer cohort.

Genomic profiling of lung adenocarcinoma and squamous carcinoma in Indian patients: Implications for precision oncology. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This ...