In the case of a short straddle, on the other hand, an investor’s potential losses are not capped and could be quite high if the price of the underlying security moves far enough away from the strike ...
Remove the rare variants, here singletons and doubletons by setting AC threshold with 'bcftools view'. Split multiallelic sites to biallelic records with 'bcftools norm'. Keep only SNPs and INDELs ...