Biology has clever ways to mask the effects of potentially harmful gene mutations. Scientists are investigating how this ...
Genetic mutations that drive cancer often occur in tumor suppressor proteins, including the p53 transcription factor which is altered in ~40-50% of cases 1,2. However, current therapies fail to target ...
In the 1960s, Kimura’s neutral theory revolutionized molecular biology by arguing most DNA changes are random, not adaptive. A new study finds beneficial mutations are far more common than Kimura’s ...